Champions Juventus took a huge step towards retaining the Serie A title by beating second-placed Napoli, with both sides reduced to 10 men, ONA reports quoting BBC.
Napoli goalkeeper Alex Meret was given a straight red card for tripping Cristiano Ronaldo and Miralem Pjanic curled in the resulting free-kick.
Emre Can headed a second, before Pjanic was dismissed for deliberate handball.
Jose Callejon pulled a goal back and Napoli's Lorenzo Insigne missed a late penalty.
The spot-kick was awarded by the VAR six minutes from time after Fabian Ruiz's cutback hit Alex Sandro on the arm, although the Juventus defender knew little about it.
Referee Gianluca Rocchi jogged over to have a look at the replay on the pitchside monitor and awarded the penalty, but Insigne rattled the post.